[Q42] 40. I am using, or have used, the following medications The following categories of drugs have some suspected or known links to higher dry eye risks. IMPORTANT: WE ARE NOT SAYING THAT THESE DRUGS CAUSE DRY EYE. Just because a drug is in a certain category that has been highlighted in a study as having a link, does not mean that the individual drug will, or is likely to, cause or contribute to dry eye, or even has dry eye listed as a potential side effect. We are asking in case this process spotlights a potential connection that you weren’t aware of and want to discuss with your eye doctor, and because trends we find in our survey may suggest further areas of research.
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Question Count Score
Never Not anymore Periodically/as needed Currently Prefer not to say (or not sure)
Certain types of blood pressure medications, e.g., metoprolol (a beta blocker), prazosin (an alpha blocker), clonidine (a central alpha agonist), hydrochlorothiazide (a diuretic) 479 1.71
Certain types of pain relievers, e.g., aspirin (an NSAID), ibuprofen (an NSAID), oxymorphone (an opioid), amitriptyline (a tricyclic antidepressant), duloxetine (an SNRI) 479 2.68
Antihistamines, e.g., azelastine, cetirizine, fexofenadine, loratadine, chlorpheniramine, diphenhydramine 479 2.17
Decongestants, e.g., pseudoephedrine, phenylephrine, phenylpropanolamine, oxymetazoline, xylometazoline 479 1.91
Bronchodilators, e.g., ipratropium, tiotropium 479 1.27
Antispasmodics and bladder/prostate relaxers, e.g., oxybutynin, tolterodine, fesoterodine, solifenacin, trospium, alfuzosin, doxazosin, tamsulosin, terazosin 479 1.16
Antidepressants, e.g., bupropion (an NDRI), protriptyline (a tricyclic antidepressant), mirtazapine (a tetracyclic antidepressant), citalopram (an SSRI), venlafaxine (an SNRI) 479 1.84
Antipsychotics, e.g., chlorpromazine (an FGA), fluphenazine (an FGA), thiothixene (an FGA), ziprasidone (an SGA), clozapine (an SGA), aripiprazole (an SGA), quetiapine (an SGA), lithium carbonate (an anti-manic agent) 479 1.05
Sedating anti-anxiety and sleep medications, e.g., alprazolam (a benzodiazepine), lorazepam (a benzodiazepine), eszopiclone (a sedative-hypnotic), zolpidem (a sedative-hypnotic)Antidepressants/antipsychotics 479 1.65
Contraceptives and hormone-replacement or hormone-suppressing medications, e.g., estrogen/progesterone, medroxyprogesterone, leuprorelin, finasterideMultivitamins 479 1.81
Cancer treatment medications, e.g., busulfan (an alkylating agent), cyclophosphamide (an alkylating agent), cetuximab (a monoclonal antibody), panitumumab (a monoclonal antibody), docetaxel (a taxane), erlotinib (an EGFR inhibitor), interferon, methotrexate (an antimetabolite), mitomycin C (an antibiotic), vinblastine (an alkaloid), verteporfin (a YAP inhibitor) 479 1.14
Bone loss treatment medications, e.g., alendronate, pamidronate, risedronate 479 1.25
Vitamin-based medications and herbal supplements, e.g., isotretinoin (acne medication), niacin, echinacea, kava 479 1.87
Something else 479 1.37
Average 1.63
Certain types of blood pressure medications, e.g., metoprolol (a beta blocker), prazosin (an alpha blocker), clonidine (a central alpha agonist), hydrochlorothiazide (a diuretic)
Answer Count Percent
20% 40% 60% 80% 100%
Never 345 72.03%
Not anymore 29 6.05%
Periodically/as needed 5 1.04%
Currently 98 20.46%
Prefer not to say (or not sure) 2 0.42%
Total 479 100 %
Certain types of pain relievers, e.g., aspirin (an NSAID), ibuprofen (an NSAID), oxymorphone (an opioid), amitriptyline (a tricyclic antidepressant), duloxetine (an SNRI)
Answer Count Percent
20% 40% 60% 80% 100%
Never 98 20.46%
Not anymore 65 13.57%
Periodically/as needed 211 44.05%
Currently 104 21.71%
Prefer not to say (or not sure) 1 0.21%
Total 479 100 %
Antihistamines, e.g., azelastine, cetirizine, fexofenadine, loratadine, chlorpheniramine, diphenhydramine
Answer Count Percent
20% 40% 60% 80% 100%
Never 187 39.04%
Not anymore 91 19%
Periodically/as needed 132 27.56%
Currently 69 14.41%
Prefer not to say (or not sure) 0 0%
Total 479 100 %
Decongestants, e.g., pseudoephedrine, phenylephrine, phenylpropanolamine, oxymetazoline, xylometazoline
Answer Count Percent
20% 40% 60% 80% 100%
Never 220 45.93%
Not anymore 94 19.62%
Periodically/as needed 151 31.52%
Currently 14 2.92%
Prefer not to say (or not sure) 0 0%
Total 479 100 %
Bronchodilators, e.g., ipratropium, tiotropium
Answer Count Percent
20% 40% 60% 80% 100%
Never 409 85.39%
Not anymore 29 6.05%
Periodically/as needed 23 4.8%
Currently 17 3.55%
Prefer not to say (or not sure) 1 0.21%
Total 479 100 %
Antispasmodics and bladder/prostate relaxers, e.g., oxybutynin, tolterodine, fesoterodine, solifenacin, trospium, alfuzosin, doxazosin, tamsulosin, terazosin
Answer Count Percent
20% 40% 60% 80% 100%
Never 439 91.65%
Not anymore 18 3.76%
Periodically/as needed 7 1.46%
Currently 15 3.13%
Prefer not to say (or not sure) 0 0%
Total 479 100 %
Antidepressants, e.g., bupropion (an NDRI), protriptyline (a tricyclic antidepressant), mirtazapine (a tetracyclic antidepressant), citalopram (an SSRI), venlafaxine (an SNRI)
Answer Count Percent
20% 40% 60% 80% 100%
Never 298 62.21%
Not anymore 69 14.41%
Periodically/as needed 8 1.67%
Currently 97 20.25%
Prefer not to say (or not sure) 7 1.46%
Total 479 100 %
Antipsychotics, e.g., chlorpromazine (an FGA), fluphenazine (an FGA), thiothixene (an FGA), ziprasidone (an SGA), clozapine (an SGA), aripiprazole (an SGA), quetiapine (an SGA), lithium carbonate (an anti-manic agent)
Answer Count Percent
20% 40% 60% 80% 100%
Never 466 97.29%
Not anymore 7 1.46%
Periodically/as needed 2 0.42%
Currently 1 0.21%
Prefer not to say (or not sure) 3 0.63%
Total 479 100 %
Sedating anti-anxiety and sleep medications, e.g., alprazolam (a benzodiazepine), lorazepam (a benzodiazepine), eszopiclone (a sedative-hypnotic), zolpidem (a sedative-hypnotic)Antidepressants/antipsychotics
Answer Count Percent
20% 40% 60% 80% 100%
Never 324 67.64%
Not anymore 55 11.48%
Periodically/as needed 47 9.81%
Currently 49 10.23%
Prefer not to say (or not sure) 4 0.84%
Total 479 100 %
Contraceptives and hormone-replacement or hormone-suppressing medications, e.g., estrogen/progesterone, medroxyprogesterone, leuprorelin, finasterideMultivitamins
Answer Count Percent
20% 40% 60% 80% 100%
Never 236 49.27%
Not anymore 165 34.45%
Periodically/as needed 13 2.71%
Currently 63 13.15%
Prefer not to say (or not sure) 2 0.42%
Total 479 100 %
Cancer treatment medications, e.g., busulfan (an alkylating agent), cyclophosphamide (an alkylating agent), cetuximab (a monoclonal antibody), panitumumab (a monoclonal antibody), docetaxel (a taxane), erlotinib (an EGFR inhibitor), interferon, methotrexate (an antimetabolite), mitomycin C (an antibiotic), vinblastine (an alkaloid), verteporfin (a YAP inhibitor)
Answer Count Percent
20% 40% 60% 80% 100%
Never 432 90.19%
Not anymore 38 7.93%
Periodically/as needed 1 0.21%
Currently 6 1.25%
Prefer not to say (or not sure) 2 0.42%
Total 479 100 %
Bone loss treatment medications, e.g., alendronate, pamidronate, risedronate
Answer Count Percent
20% 40% 60% 80% 100%
Never 417 87.06%
Not anymore 34 7.1%
Periodically/as needed 1 0.21%
Currently 25 5.22%
Prefer not to say (or not sure) 2 0.42%
Total 479 100 %
Vitamin-based medications and herbal supplements, e.g., isotretinoin (acne medication), niacin, echinacea, kava
Answer Count Percent
20% 40% 60% 80% 100%
Never 309 64.51%
Not anymore 35 7.31%
Periodically/as needed 30 6.26%
Currently 98 20.46%
Prefer not to say (or not sure) 7 1.46%
Total 479 100 %
Something else
Answer Count Percent
20% 40% 60% 80% 100%
Never 415 86.64%
Not anymore 7 1.46%
Periodically/as needed 4 0.84%
Currently 50 10.44%
Prefer not to say (or not sure) 3 0.63%
Total 479 100 %
Something else - Dynamic Text / Comments
02/26/2021 102406585 [Not anymore] Acutane for acne
02/25/2021 102186447 [Periodically/as needed] Hypnotherapy
02/23/2021 101873065 [Currently] Cancer treatment med: Lymparza (olabarib)
02/21/2021 101633186 [Periodically/as needed] Eliquis (anti-coagulant); propafenone (anti-arrhythmic)
02/19/2021 101528426 [Currently] Was on Humira for close to 10 years, now getting Entyvvio infusions. I take desipramine in very small amt. for severe IBS, so not for depression (I only take 30 mg, depression dose is 100-300mg) I also tale an anti-cholinergic (Hyosycamine ER )when needed but was very ill recently and have been having to take it routinely every night
02/19/2021 101523339 [Currently] She has several meds related to her condition
02/12/2021 100730864 [Currently] Ketotifen Fumarate; LDN; cromolyn sodium, fish oil, vitamin D, K, Vitamin C, L methylfolate, B-12 oils, probiotics
02/08/2021 100191099 [Currently] Anastrozole
02/05/2021 99961749 [Currently] B-12, D, Fish/Flax Oil
02/05/2021 99928278 [Currently] Lotion with 5% minoxidil and 2% finasteride for treating hair loss. I am using it for 3 years but noticed no change in dry eye that I experienced before starting shedding (now I feel better both eye and hair).